1D TOCSY for Mixture Analysis

Many two dimensional techniques such as the 2D TOCSY, have similar 1D analogs where selective pulses are used to get effectively only one slice of the comparable 2D experiment. If you are only interested in a few correlations, then the 1D experiments can represent a tremendous time saving ( i.e. money saving). Below is a series of 1D TOCSY spectra run on a mixture of toluene, p-dichlorobenzene and pyridine. In this case, the technique can be used to separate out the components of the mixture. In the figure, the lower trace is the standard ¹H spectrum. In the other traces red arrows indicate the resonance selectively irradiated with the shaped pulse.