tag:blogger.com,1999:blog-3300702123878659843.post3164942293032132112..comments2024-03-17T03:38:56.391-04:00Comments on University of Ottawa NMR Facility Blog: Measuring 2H NMR SpectraGlenn Faceyhttp://www.blogger.com/profile/05146575170575279335noreply@blogger.comBlogger7125tag:blogger.com,1999:blog-3300702123878659843.post-45456093124167915302019-03-19T17:48:06.342-04:002019-03-19T17:48:06.342-04:00Anonymous,
Here are some data on T1's and T2...Anonymous, <br /><br />Here are some data on T1's and T2's (Table S1 in link below).<br />It's probably limited for what you need, as this is focused on in vivo 2H NMR. The values were measured on a preclinical 11.7 T MRI scanner. <br /><br />http://advances.sciencemag.org/content/advances/suppl/2018/08/20/4.8.eaat7314.DC1/aat7314_SM.pdf<br /><br />Henkhenkhttps://www.blogger.com/profile/00327110070625807295noreply@blogger.comtag:blogger.com,1999:blog-3300702123878659843.post-58259254497748305592019-01-15T08:20:27.465-05:002019-01-15T08:20:27.465-05:00MS,
The the most significant mechanism for 2H rela...MS,<br />The the most significant mechanism for 2H relaxation is quadrupolar rather than dipolar. The 2H T1 could be either longer or shorter than the T1 of a comparable proton. Unfortunately I do not have a table of 2H T1's on hand. It may be easier to just estimate it as described here https://u-of-o-nmr-facility.blogspot.com/2007/10/t1-measurements-and-estimation.html .<br /><br />GlennGlenn Faceyhttps://www.blogger.com/profile/05146575170575279335noreply@blogger.comtag:blogger.com,1999:blog-3300702123878659843.post-73148626560781831362019-01-15T07:19:09.488-05:002019-01-15T07:19:09.488-05:00Dear Glenn,
Thanks a lot for this form! I was jus...Dear Glenn, <br />Thanks a lot for this form! I was just looking for some examples of T1 times of 2H nuclei. You mention T1's a s well. Do you have some numbers or at a range. What are save interscan delays?<br />With best regards, MSAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-3300702123878659843.post-44779354526233233472018-02-17T08:52:10.243-05:002018-02-17T08:52:10.243-05:00VNM
See this post
http://u-of-o-nmr-facility.blog...VNM<br /><br />See this post<br />http://u-of-o-nmr-facility.blogspot.ca/2008/05/consequence-of-locking-on-wrong-solvent.html<br /><br />GlennGlenn Faceyhttps://www.blogger.com/profile/05146575170575279335noreply@blogger.comtag:blogger.com,1999:blog-3300702123878659843.post-29200462093575552502018-02-17T04:35:45.769-05:002018-02-17T04:35:45.769-05:00Dear Glenn Facey,
In my one of the NMR, the d...Dear Glenn Facey,<br /><br /> In my one of the NMR, the deuterated solvent was given wrong by the operator. For example, it was given D2O in place of CDCl3. Was that fine ? or I should ask them to record again with appropriate deuterated solvent. How does it affect the locking and chemical shift value ? Please explain !!<br /><br />with thanks<br />VNM nareshhttps://www.blogger.com/profile/10685895251219813963noreply@blogger.comtag:blogger.com,1999:blog-3300702123878659843.post-39902527623705181652016-11-28T11:16:22.553-05:002016-11-28T11:16:22.553-05:00Anonymous,
Provided that you respect the T1's...Anonymous,<br /><br />Provided that you respect the T1's, you should be able to get quantitative data.<br /><br />GlennGlenn Faceyhttps://www.blogger.com/profile/05146575170575279335noreply@blogger.comtag:blogger.com,1999:blog-3300702123878659843.post-85837217635782667192016-11-18T21:43:39.288-05:002016-11-18T21:43:39.288-05:00Not proud to admit it, but when I got an instructi...Not proud to admit it, but when I got an instruction on how to measure 2H NMR a while back in a different millennium, our NMR instructor asked me to prepare a demo sample for the occasion. Of course I dissolved the deuterated sample in CDCl3... and of course the instructor had not warned me beforehand, but let me walk right into the trap. <br />If I remember correctly we had to manually swap a few cable connections to use the lock-channel to record the 2H signal, and use a screwdriver to tune the channel, and so on.<br /><br />Anyway, back to present: I do an 1H-decoupled 2H NMR and want to use a small amount (10 μL) of C6D6 as internal standard for quantification. Do you know anything about doing quantitative 2H NMR with deuterated internal standards? Can I expect good results?Anonymousnoreply@blogger.com